Lithium Determination Helps Optimize Treatment and Avoid Toxicity
Lithium has a narrow therapeutic and toxic range and causes kidney damage in some patients. A kit is intended for the quantitative in vitro determination of lithium in serum and is suitable for use on a wide range of clinical analyzers. The new reagent is liquid stable for ease of use and offers an improved open vial stability of 14 days at 10 °C. Other features include a wide measuring range of 0.281 mmol/L -3.00 mmol/L, precision, traceability to the National Institute of Standards and Technology (NIST; Gaithersburg, MD, USA; www.nist.gov] reference method, and limited interference from bilirubin, triglycerides, and hemoglobin. A product of Randox (Crumlin, UK; www.randox.com] the lithium kit augments a wide range of tests for monitoring the use of drugs with very small therapeutic ranges.